two-way analysis of variance with dunnett’s multiple comparisons test Search Results


usp15 sirna  (Viromer Transfection)
90
Viromer Transfection usp15 sirna
Usp15 Sirna, supplied by Viromer Transfection, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/two-way+analysis+of+variance+with+dunnett%E2%80%99s+multiple+comparisons+test/usp15+sirna/pm37874479-366-12-36
Average 90 stars, based on 1 article reviews
usp15 sirna - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
cem transfection method  (CEM Corporation)
90
CEM Corporation cem transfection method
Sequence used in this study and melting temperature ( T m ) of ASO/RNA or ASO/PNA
Cem Transfection Method, supplied by CEM Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/two-way+analysis+of+variance+with+dunnett%E2%80%99s+multiple+comparisons+test/cem+transfection+method/pmc10693639-225-103-102
Average 90 stars, based on 1 article reviews
cem transfection method - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
chi-square analysis  (CH Instruments)
90
CH Instruments chi-square analysis
Sequence used in this study and melting temperature ( T m ) of ASO/RNA or ASO/PNA
Chi Square Analysis, supplied by CH Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/two-way+analysis+of+variance+with+dunnett%E2%80%99s+multiple+comparisons+test/chi+square+analysis/10__1038_slash_nchembio__1930-701-13-6
Average 90 stars, based on 1 article reviews
chi-square analysis - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
two way anova by sas  (SAS institute)
97
SAS institute two way anova by sas
Sequence used in this study and melting temperature ( T m ) of ASO/RNA or ASO/PNA
Two Way Anova By Sas, supplied by SAS institute, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/two-way+analysis+of+variance+with+dunnett%E2%80%99s+multiple+comparisons+test/SAS+Model+Risk+Management/pm19483322-122-9-12
Average 97 stars, based on 1 article reviews
two way anova by sas - by Bioz Stars, 2026-10
97/100 stars
  Buy from Supplier
odyssey imaging system  (LI-COR)
99
LI-COR odyssey imaging system
Sequence used in this study and melting temperature ( T m ) of ASO/RNA or ASO/PNA
Odyssey Imaging System, supplied by LI-COR, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/two-way+analysis+of+variance+with+dunnett%E2%80%99s+multiple+comparisons+test/Odyssey+Imaging+System/custom%40odyssey-imaging-system%4037175448
Average 99 stars, based on 1 article reviews
odyssey imaging system - by Bioz Stars, 2026-10
99/100 stars
  Buy from Supplier
odyssey  (LI-COR)
99
LI-COR odyssey
Sequence used in this study and melting temperature ( T m ) of ASO/RNA or ASO/PNA
Odyssey, supplied by LI-COR, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/two-way+analysis+of+variance+with+dunnett%E2%80%99s+multiple+comparisons+test/Odyssey/custom%40Odyssey%4037175448
Average 99 stars, based on 1 article reviews
odyssey - by Bioz Stars, 2026-10
99/100 stars
  Buy from Supplier
keyplot5.0  (KyensLab Inc)
90
KyensLab Inc keyplot5.0
Sequence used in this study and melting temperature ( T m ) of ASO/RNA or ASO/PNA
Keyplot5.0, supplied by KyensLab Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/two-way+analysis+of+variance+with+dunnett%E2%80%99s+multiple+comparisons+test/keyplot5+0/pm38642892-253-14-17
Average 90 stars, based on 1 article reviews
keyplot5.0 - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
originpro 8  (OriginLab corp)
90
OriginLab corp originpro 8
Sequence used in this study and melting temperature ( T m ) of ASO/RNA or ASO/PNA
Originpro 8, supplied by OriginLab corp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/two-way+analysis+of+variance+with+dunnett%E2%80%99s+multiple+comparisons+test/originpro+software/pmc09093067-157-18-23
Average 90 stars, based on 1 article reviews
originpro 8 - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
origin 9.1  (KyensLab Inc)
90
KyensLab Inc origin 9.1
Sequence used in this study and melting temperature ( T m ) of ASO/RNA or ASO/PNA
Origin 9.1, supplied by KyensLab Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/two-way+analysis+of+variance+with+dunnett%E2%80%99s+multiple+comparisons+test/origin+9+1/pmc11134551-334-15-19
Average 90 stars, based on 1 article reviews
origin 9.1 - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
paired and unpaired student’s t -tests  (KyensLab Inc)
90
KyensLab Inc paired and unpaired student’s t -tests
Sequence used in this study and melting temperature ( T m ) of ASO/RNA or ASO/PNA
Paired And Unpaired Student’s T Tests, supplied by KyensLab Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/two-way+analysis+of+variance+with+dunnett%E2%80%99s+multiple+comparisons+test/paired+and+unpaired+student%E2%80%99s+t++tests/pmc09695908-177-17-27
Average 90 stars, based on 1 article reviews
paired and unpaired student’s t -tests - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
origin software  (OriginLab corp)
90
OriginLab corp origin software
Sequence used in this study and melting temperature ( T m ) of ASO/RNA or ASO/PNA
Origin Software, supplied by OriginLab corp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/two-way+analysis+of+variance+with+dunnett%E2%80%99s+multiple+comparisons+test/origin+software/pm24747641-442-12-14
Average 90 stars, based on 1 article reviews
origin software - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
chi-square test  (CH Instruments)
90
CH Instruments chi-square test
Sequence used in this study and melting temperature ( T m ) of ASO/RNA or ASO/PNA
Chi Square Test, supplied by CH Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/two-way+analysis+of+variance+with+dunnett%E2%80%99s+multiple+comparisons+test/chi+square+test/pmc10086529-219-58-58
Average 90 stars, based on 1 article reviews
chi-square test - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

Image Search Results


Sequence used in this study and melting temperature ( T m ) of ASO/RNA or ASO/PNA

Journal: Nature Communications

Article Title: Dynamic and static control of the off-target interactions of antisense oligonucleotides using toehold chemistry

doi: 10.1038/s41467-023-43714-0

Figure Lengend Snippet: Sequence used in this study and melting temperature ( T m ) of ASO/RNA or ASO/PNA

Article Snippet: Fig. 6 Complementary PNAs suppress off-target hybridizations. a Schematic illustration of an in-cuvette FRET assay. b Hybridization kinetics were evaluated for the indicated ssASO and BROs using FRET ( n = 3 independent experiments). c The antisense effects of hApo1n/PNA(C9) and hApo1n/cGapmer on ApoB mRNA in Huh-7 cells using the CEM transfection method ( n = 6 biologically independent samples for control, n = 3 for BRO series; one-way ANOVA followed by two-sided Dunnett’s multiple comparison tests comparing to control, p values from left side; <0.0001, 0.0006, 0.6547). d The antisense effects of hApo1n and hApo1n/PNA(C5-C13) BROs in Huh-7 cells using the CEM transfection method ( n = 3 biologically independent samples; one-way ANOVA followed by two-sided Dunnett’s multiple comparison tests comparing to hApo1n, p values from left side; <0.0001, 0.9854, 0.99398, 0.4175, 0.0388, 0.0011, <0.0001, <0.0001, <0.0001, <0.0001). e The van’t Hoff analysis for the indicated ssASO and BROs ( n = 3 independent experiments). f Knockdown activities of on-target ApoB gene and three single-mismatch genes were compared for indicated hApo1n and BROs (hApo1n/PNA(C8), hApo1n/PNA(C9)) in Huh-7 cells exposed to 1 µM after 24 h of CEM transfection ( n = 3 biologically independent samples; one-way ANOVA followed by two-sided Dunnett’s multiple comparison tests comparing to control, p values from left side; ApoB: <0.0001, <0.0001, <0.0001; Copg: 0.0299, 0.1307, 0.1071; Mast2: 0.0012, 0.1826, 0.8253; Hltf: 0.0262, 0.9132, 0.4780). g Hybridization kinetics for on-target mRNA ( ApoB ) were evaluated for the indicated ssASO and BROs using FRET ( n = 3 independent experiments). h FRET assay of TAMRA-labeled hApo1nF and BHQ2-labeled mRNA mimics (Copg, Hltf). i FRET assay of TAMRA-labeled hApo1nF/PNA(C9) BRO and BHQ2-labeled mRNA mimics (Copg, Hltf).

Techniques: Sequencing

a Procedure for evaluation of cytotoxicity of mPCS1n ssASO and mPCS1n/PNA(C8) BRO in original and galactose-modified media. b PI staining of Huh-7 cells exposed to 2 µM mPCS1n ssASO and mPCS1n/PNA(C8) BRO after 48 h of CEM transfection ( n = 3 biologically independent samples). c Drug concentration-dependent assessment of cell viability ( n = 5 biologically independent samples) d Activity of caspases 3/7, 8, and 9 ( n = 4 biologically independent samples; one-way ANOVA followed by two-sided Dunnett’s multiple comparison tests comparing to control, p values from left side; glucose conditions: 0.0674, 0.5360 for caspase 8; 0.0077, 0.9104 for caspase 9; 0.032, 0.9571 for caspase 3/7; galactose conditions: <0.0001, 0.8379 for caspase 8; <0.0001, 0.7712 for caspase 9; <0.0001, 0.7933 for caspase 3/7). e the depolarization of the mitochondrial membrane potential (ΔΨm) with JC−1 dye were compared and evaluated for mPCS1n or mPCS1n/PNA(C8) BRO through transfection into Huh-7 cells using the CEM method ( n = 1) ( e ). ** p < 0.01, * p < 0.05. “ns” indicates not significant ( p > 0.05). Data in Fig. 4c and d are presented as mean values ± SD. Source data are provided as a Source Data file.

Journal: Nature Communications

Article Title: Dynamic and static control of the off-target interactions of antisense oligonucleotides using toehold chemistry

doi: 10.1038/s41467-023-43714-0

Figure Lengend Snippet: a Procedure for evaluation of cytotoxicity of mPCS1n ssASO and mPCS1n/PNA(C8) BRO in original and galactose-modified media. b PI staining of Huh-7 cells exposed to 2 µM mPCS1n ssASO and mPCS1n/PNA(C8) BRO after 48 h of CEM transfection ( n = 3 biologically independent samples). c Drug concentration-dependent assessment of cell viability ( n = 5 biologically independent samples) d Activity of caspases 3/7, 8, and 9 ( n = 4 biologically independent samples; one-way ANOVA followed by two-sided Dunnett’s multiple comparison tests comparing to control, p values from left side; glucose conditions: 0.0674, 0.5360 for caspase 8; 0.0077, 0.9104 for caspase 9; 0.032, 0.9571 for caspase 3/7; galactose conditions: <0.0001, 0.8379 for caspase 8; <0.0001, 0.7712 for caspase 9; <0.0001, 0.7933 for caspase 3/7). e the depolarization of the mitochondrial membrane potential (ΔΨm) with JC−1 dye were compared and evaluated for mPCS1n or mPCS1n/PNA(C8) BRO through transfection into Huh-7 cells using the CEM method ( n = 1) ( e ). ** p < 0.01, * p < 0.05. “ns” indicates not significant ( p > 0.05). Data in Fig. 4c and d are presented as mean values ± SD. Source data are provided as a Source Data file.

Article Snippet: Fig. 6 Complementary PNAs suppress off-target hybridizations. a Schematic illustration of an in-cuvette FRET assay. b Hybridization kinetics were evaluated for the indicated ssASO and BROs using FRET ( n = 3 independent experiments). c The antisense effects of hApo1n/PNA(C9) and hApo1n/cGapmer on ApoB mRNA in Huh-7 cells using the CEM transfection method ( n = 6 biologically independent samples for control, n = 3 for BRO series; one-way ANOVA followed by two-sided Dunnett’s multiple comparison tests comparing to control, p values from left side; <0.0001, 0.0006, 0.6547). d The antisense effects of hApo1n and hApo1n/PNA(C5-C13) BROs in Huh-7 cells using the CEM transfection method ( n = 3 biologically independent samples; one-way ANOVA followed by two-sided Dunnett’s multiple comparison tests comparing to hApo1n, p values from left side; <0.0001, 0.9854, 0.99398, 0.4175, 0.0388, 0.0011, <0.0001, <0.0001, <0.0001, <0.0001). e The van’t Hoff analysis for the indicated ssASO and BROs ( n = 3 independent experiments). f Knockdown activities of on-target ApoB gene and three single-mismatch genes were compared for indicated hApo1n and BROs (hApo1n/PNA(C8), hApo1n/PNA(C9)) in Huh-7 cells exposed to 1 µM after 24 h of CEM transfection ( n = 3 biologically independent samples; one-way ANOVA followed by two-sided Dunnett’s multiple comparison tests comparing to control, p values from left side; ApoB: <0.0001, <0.0001, <0.0001; Copg: 0.0299, 0.1307, 0.1071; Mast2: 0.0012, 0.1826, 0.8253; Hltf: 0.0262, 0.9132, 0.4780). g Hybridization kinetics for on-target mRNA ( ApoB ) were evaluated for the indicated ssASO and BROs using FRET ( n = 3 independent experiments). h FRET assay of TAMRA-labeled hApo1nF and BHQ2-labeled mRNA mimics (Copg, Hltf). i FRET assay of TAMRA-labeled hApo1nF/PNA(C9) BRO and BHQ2-labeled mRNA mimics (Copg, Hltf).

Techniques: Modification, Staining, Transfection, Concentration Assay, Activity Assay, Comparison, Membrane

a Schematic illustration of an in-cuvette FRET assay. b Hybridization kinetics were evaluated for the indicated ssASO and BROs using FRET ( n = 3 independent experiments). c The antisense effects of hApo1n/PNA(C9) and hApo1n/cGapmer on ApoB mRNA in Huh-7 cells using the CEM transfection method ( n = 6 biologically independent samples for control, n = 3 for BRO series; one-way ANOVA followed by two-sided Dunnett’s multiple comparison tests comparing to control, p values from left side; <0.0001, 0.0006, 0.6547). d The antisense effects of hApo1n and hApo1n/PNA(C5-C13) BROs in Huh-7 cells using the CEM transfection method ( n = 3 biologically independent samples; one-way ANOVA followed by two-sided Dunnett’s multiple comparison tests comparing to hApo1n, p values from left side; <0.0001, 0.9854, 0.99398, 0.4175, 0.0388, 0.0011, <0.0001, <0.0001, <0.0001, <0.0001). e The van’t Hoff analysis for the indicated ssASO and BROs ( n = 3 independent experiments). f Knockdown activities of on-target ApoB gene and three single-mismatch genes were compared for indicated hApo1n and BROs (hApo1n/PNA(C8), hApo1n/PNA(C9)) in Huh-7 cells exposed to 1 µM after 24 h of CEM transfection ( n = 3 biologically independent samples; one-way ANOVA followed by two-sided Dunnett’s multiple comparison tests comparing to control, p values from left side; ApoB: <0.0001, <0.0001, <0.0001; Copg: 0.0299, 0.1307, 0.1071; Mast2: 0.0012, 0.1826, 0.8253; Hltf: 0.0262, 0.9132, 0.4780). g Hybridization kinetics for on-target mRNA ( ApoB ) were evaluated for the indicated ssASO and BROs using FRET ( n = 3 independent experiments). h FRET assay of TAMRA-labeled hApo1nF and BHQ2-labeled mRNA mimics (Copg, Hltf). i FRET assay of TAMRA-labeled hApo1nF/PNA(C9) BRO and BHQ2-labeled mRNA mimics (Copg, Hltf). Data in Fig. 6b–d and g–i are presented as mean values ± SD. ** p < 0.01, * p < 0.05. “ns” indicates not significant ( p > 0.05). Source data are provided as a Source Data file.

Journal: Nature Communications

Article Title: Dynamic and static control of the off-target interactions of antisense oligonucleotides using toehold chemistry

doi: 10.1038/s41467-023-43714-0

Figure Lengend Snippet: a Schematic illustration of an in-cuvette FRET assay. b Hybridization kinetics were evaluated for the indicated ssASO and BROs using FRET ( n = 3 independent experiments). c The antisense effects of hApo1n/PNA(C9) and hApo1n/cGapmer on ApoB mRNA in Huh-7 cells using the CEM transfection method ( n = 6 biologically independent samples for control, n = 3 for BRO series; one-way ANOVA followed by two-sided Dunnett’s multiple comparison tests comparing to control, p values from left side; <0.0001, 0.0006, 0.6547). d The antisense effects of hApo1n and hApo1n/PNA(C5-C13) BROs in Huh-7 cells using the CEM transfection method ( n = 3 biologically independent samples; one-way ANOVA followed by two-sided Dunnett’s multiple comparison tests comparing to hApo1n, p values from left side; <0.0001, 0.9854, 0.99398, 0.4175, 0.0388, 0.0011, <0.0001, <0.0001, <0.0001, <0.0001). e The van’t Hoff analysis for the indicated ssASO and BROs ( n = 3 independent experiments). f Knockdown activities of on-target ApoB gene and three single-mismatch genes were compared for indicated hApo1n and BROs (hApo1n/PNA(C8), hApo1n/PNA(C9)) in Huh-7 cells exposed to 1 µM after 24 h of CEM transfection ( n = 3 biologically independent samples; one-way ANOVA followed by two-sided Dunnett’s multiple comparison tests comparing to control, p values from left side; ApoB: <0.0001, <0.0001, <0.0001; Copg: 0.0299, 0.1307, 0.1071; Mast2: 0.0012, 0.1826, 0.8253; Hltf: 0.0262, 0.9132, 0.4780). g Hybridization kinetics for on-target mRNA ( ApoB ) were evaluated for the indicated ssASO and BROs using FRET ( n = 3 independent experiments). h FRET assay of TAMRA-labeled hApo1nF and BHQ2-labeled mRNA mimics (Copg, Hltf). i FRET assay of TAMRA-labeled hApo1nF/PNA(C9) BRO and BHQ2-labeled mRNA mimics (Copg, Hltf). Data in Fig. 6b–d and g–i are presented as mean values ± SD. ** p < 0.01, * p < 0.05. “ns” indicates not significant ( p > 0.05). Source data are provided as a Source Data file.

Article Snippet: Fig. 6 Complementary PNAs suppress off-target hybridizations. a Schematic illustration of an in-cuvette FRET assay. b Hybridization kinetics were evaluated for the indicated ssASO and BROs using FRET ( n = 3 independent experiments). c The antisense effects of hApo1n/PNA(C9) and hApo1n/cGapmer on ApoB mRNA in Huh-7 cells using the CEM transfection method ( n = 6 biologically independent samples for control, n = 3 for BRO series; one-way ANOVA followed by two-sided Dunnett’s multiple comparison tests comparing to control, p values from left side; <0.0001, 0.0006, 0.6547). d The antisense effects of hApo1n and hApo1n/PNA(C5-C13) BROs in Huh-7 cells using the CEM transfection method ( n = 3 biologically independent samples; one-way ANOVA followed by two-sided Dunnett’s multiple comparison tests comparing to hApo1n, p values from left side; <0.0001, 0.9854, 0.99398, 0.4175, 0.0388, 0.0011, <0.0001, <0.0001, <0.0001, <0.0001). e The van’t Hoff analysis for the indicated ssASO and BROs ( n = 3 independent experiments). f Knockdown activities of on-target ApoB gene and three single-mismatch genes were compared for indicated hApo1n and BROs (hApo1n/PNA(C8), hApo1n/PNA(C9)) in Huh-7 cells exposed to 1 µM after 24 h of CEM transfection ( n = 3 biologically independent samples; one-way ANOVA followed by two-sided Dunnett’s multiple comparison tests comparing to control, p values from left side; ApoB: <0.0001, <0.0001, <0.0001; Copg: 0.0299, 0.1307, 0.1071; Mast2: 0.0012, 0.1826, 0.8253; Hltf: 0.0262, 0.9132, 0.4780). g Hybridization kinetics for on-target mRNA ( ApoB ) were evaluated for the indicated ssASO and BROs using FRET ( n = 3 independent experiments). h FRET assay of TAMRA-labeled hApo1nF and BHQ2-labeled mRNA mimics (Copg, Hltf). i FRET assay of TAMRA-labeled hApo1nF/PNA(C9) BRO and BHQ2-labeled mRNA mimics (Copg, Hltf).

Techniques: Hybridization, Transfection, Comparison, Labeling